Eric Dane joined Valentine's Day playing a (closet?) quarterback.

"Grey's Anatomy's hunky docs Patrick Dempsey and Eric Dane will costar on the big-screen. The Hollywood Reporter and Variety have independently reported that Dempsey and Dane, respectively, have joined director Garry Marshall's ensemble comedy Valentine's Day. Dane will play a Brett Favre-esque quarterback, and Dempsey will play a cheating doctor in this collection of intersecting romances, alongside Julia Roberts, Anne Hathaway, Jessica Alba, Jessica Biel, Jennifer Garner, Shirley MacLaine, Bradley Cooper, Ashton Kutcher, Topher Grace, Emma Roberts and Hector Elizondo."

http://news-briefs.ew.com/2009/07/dempsey-dane-costar-in-valentines-day.html

This go with what Afterelton reported Bradley Cooper's character lover is a closeted football player.

"Julia Roberts, Anne Hathaway, Jessica Alba, Jessica Biel, Jennifer Garner, Shirley MacLaine, Bradley Cooper and Ashton Kutcher are in final negotiations to star in the movie, which has five slightly interconnecting stories playing out during a Valentine's Day in Los Angeles.

Roberts is an army officer on leave from Iraq on a flight to L.A. Cooper, on the same flight, is a gay man whose lover is a closeted football player."

http://www.afterelton.com/blog/snicks/afterelton-fantasy-casting-who-should-steal-bradley-coopers-heart-in-valentines-day